I'd say that if a specific genetic trait makes rattlers in a certain region far more dangerous than others, it's time for a rattlesnake round up. Let's get the biting going in the other direction - I hear they taste like chicken!
All kidding aside, reducing that population's numbers would be a good idea, and the non-venomous snakes, along with more mildly venomous pit vipers, would replace them in short order.
Of course, the tricky part would be selecting only the specific species that happens to be unusually toxic, and then culling the herd (as it were) without having people get themselves bit or having people go hog wild and kill every snake they can find.
Maybe I'm not the best judge, since I hate deadly snakes, deadly spiders, etc. Not much sympathy here!
z