Howdy Alan
The following information is from one of my continuing education courses.
If you have any trouble sleeping, read this prior to going to bed tonight
Muscle glycogen represents the major source of carbohydrate in the body (300 to 400 g or 1,200 to 1,600 kcal), followed by liver glycogen (75 to 100 g or 300 to 400 kcal) and, lastly, blood glucose (25 g or 100 kcal). These amounts vary widely among individuals, depending on factors such as dietary intake and state of training.
Untrained individuals have muscle glycogen stores that are roughly 80 to 90 mmol/kg of wet muscle weight. Endurance athletes have muscle glycogen stores of 130 to 135 mmol/kg of wet muscle weight. Carbohydrate loading increases muscle glycogen stores to 210 to 230 mmol/kg of wet muscle weight.
Exercise energetics dictate that carbohydrate is the predominant fuel for exercise intensities at and above 65% of VO2max—the levels at which most athletes train and compete. Although both carbohydrate and fat contribute to energy production during exercise, fat oxidation alone cannot supply adenosine triphosphate (ATP) rapidly enough to support such high-intensity exercise. While it is possible to exercise at light to moderate levels (<60% of VO2max) with low levels of muscle glycogen and blood glucose, it is impossible to meet the ATP requirements necessary for high intensity, high power output exercise when these fuels are depleted.
Utilization of muscle glycogen is most rapid during the early stages of exercise and is exponentially related to exercise intensity. There is a strong relationship between the pre-exercise muscle glycogen content and the length of time that exercise can be performed at 70% of VO2max. The greater the pre-exercise glycogen content, the greater the endurance potential.
Bergstrom et al measured muscle glycogen content and compared the exercise time to exhaustion at 75% of VO2max after 3 days of three diets varying in carbohydrate content. A low-carbohydrate diet (less than 5% of calories from carbohydrate) produced a muscle glycogen content of 38 mmol/kg and supported only 1 hour of exercise. A mixed diet (50% calories from carbohydrate) produced a muscle glycogen content of 106 mmol/kg and enabled the subjects to exercise 115 minutes. However, a high-carbohydrate diet (82% of calories from carbohydrate) provided 204 mmol/kg of muscle glycogen and enabled the subjects to exercise for 170 minutes.
Liver glycogen stores maintain blood glucose levels both at rest and during exercise. At rest, the brain and central nervous system (CNS) utilize most of the blood glucose, and the muscle accounts for less than 20% of blood glucose utilization. During exercise, however, muscle glucose uptake can increase 30-fold, depending on exercise intensity and duration. Initially, the majority of hepatic glucose output comes from glycogenolysis; however, as the exercise duration increases and liver glycogen declines, the contribution of glucose from gluconeogenesis increases.
At the beginning of exercise, hepatic glucose output matches the increased muscle glucose uptake so that blood glucose levels remain near resting levels. Although muscle glycogen is the primary source of carbohydrate during exercise intensities above 65% of VO2max, blood glucose becomes an increasingly important source of carbohydrate as muscle glycogen stores decline. When hepatic glucose output can no longer keep up with muscle glucose uptake during prolonged exercise, the blood glucose drops. While a few athletes experience central nervous system symptoms typical of hypoglycemia, most athletes note local muscular fatigue and have to reduce their exercise intensity (3).
Liver glycogen stores can be emptied by a 15-hour fast and can fall from a typical level of 490 mmol on a mixed diet to 60 mmol on a low-carbohydrate diet. A high-carbohydrate diet can increase liver glycogen content to about 900 mmol.
Miles of smiles,
Ellen